Skip to main content

CVS Health to Split in Two, Separating Aetna and Caremark From 9,000 Pharmacies

by Virginia M. Tjan, MD | Nov 09, 2026
CVS Health logo displayed on the glass facade of a modern office building.
Photo Source: Adobe Stock Image

CVS Health announced Wednesday, November 4, 2026, that it plans to split into two publicly traded companies, separating its Aetna health insurance and Caremark prescription drug businesses from approximately 9,000 retail pharmacies. The breakup would unwind a nearly decade-old strategy of combining insurance, drug benefits and pharmacy services under one corporation.

The separation, expected to be completed in the first half of 2028, would leave Aetna, CVS Caremark, CVS Specialty, Oak Street Health and Signify Health under the CVS Health name. A second company, CVS Pharmacy, would operate the retail stores, mail-order pharmacies, MinuteClinic locations and Health100 technology business.

CVS Chairman and CEO David Joyner would remain in charge of the healthcare company, while Group President Prem Shah would lead CVS Pharmacy. Existing shareholders would receive stakes in both businesses through a separation intended to be tax-free for CVS Health and its shareholders.

The decision reverses the expansion that led CVS to acquire Aetna in a $69 billion merger in 2018. The deal brought one of the nation’s largest health insurers under the same ownership as a major pharmacy chain and pharmacy benefit manager. CVS promoted the combination as a way to reduce healthcare costs by coordinating insurance coverage, prescriptions and patient care.

The acquisition faced federal antitrust scrutiny. The Justice Department required Aetna to sell its individual Medicare Part D prescription drug plan business to WellCare Health Plans before the merger could proceed, citing concerns about competition in the Medicare prescription drug insurance market.

Eight years later, CVS is moving to separate its retail pharmacies from Caremark and Aetna as federal regulators continue examining how pharmacy benefit managers influence prescription drug prices and competition.

In July, the Federal Trade Commission reached a settlement agreement with Caremark over allegations that its rebate practices helped inflate insulin list prices. Regulators accused Caremark and other major pharmacy benefit managers of favoring higher-priced drugs that offered larger manufacturer rebates, potentially increasing costs for patients whose copays or coinsurance were tied to those prices.

The proposed settlement requires Caremark to change several business practices, increase transparency and offer arrangements intended to lower patients’ out-of-pocket prescription costs and improve payment options for community pharmacies. The FTC has estimated that the changes could produce billions of dollars in consumer savings over the next decade.

CVS said the breakup follows stronger financial performance and would give its healthcare and retail pharmacy businesses greater freedom to pursue separate strategies. Joyner disputed suggestions that regulatory pressure drove the decision.

The announcement came as CVS reported third-quarter revenue of $108.4 billion, an increase of 5.4% from a year earlier, and raised its full-year earnings forecast. Despite those results, shares fell 12.5% on Wednesday, erasing nearly $15 billion in market value as investors assessed the company’s plans.

For patients and customers, the separation is not expected to create an immediate change in how prescriptions, insurance coverage or clinic services are provided. CVS said its businesses will continue operating as they do today during the transition.

Once independent, CVS Pharmacy would also be able to pursue relationships with health insurers, pharmacy benefit managers and drug manufacturers outside the current CVS Health corporate structure.

The breakup still requires final approval from CVS Health’s board, an effective registration statement with the Securities and Exchange Commission and confirmation of the transaction’s intended federal tax treatment. If those conditions are met, the two companies are expected to begin operating independently in the first half of 2028.

Share This Article

If you found this article insightful, consider sharing it with your network.

Virginia M. Tjan, MD
Dr. Virginia Tjan, MD, is a physician and Law Commentary journalist who brings a medical perspective to reporting on healthcare, patient care, and issues at the intersection of medicine and the law. Her clinical work focuses on the diagnosis and treatment of complex cancers, with particular experience in breast cancer, lung cancer, colorectal cancer, and multiple myeloma. She has worked with patients throughout the course of cancer care, from initial diagnosis through treatment of advanced disease, including chemotherapy, infusion therapy, diagnostic monitoring, and the management of treatment-related complications. Through her contributions to Law Commentary, Dr. Tjan helps readers better understand medical developments and healthcare issues that carry legal, regulatory, and public policy implications.

Related Articles

Pharmacy worker holds a blister pack of blue-and-white capsules while reaching for a medication box on a pharmacy shelf.

Trump Administration Orders Drug Middlemen to Reveal Fees and Profits

The Trump administration finalized a federal rule Thursday requiring pharmacy benefit managers to reveal how much money they collect from drugmakers, pharmacies and employer health plans, including rebates, fees and profits tied to prescription drug pricing arrangements. The new requirements also give large self-insured health plans the right to independently... Read More about Trump Administration Orders Drug Middlemen to Reveal Fees and Profits

Walmart logo on the side of a white building with a clear blue sky behind.

Walmart to Pay $50 Million to Settle DOJ Lawsuit Over Invalid Opioid Prescriptions

Walmart has agreed to pay $50 million to settle a Justice Department lawsuit accusing its pharmacies of knowingly filling thousands of invalid prescriptions for opioids and other controlled substances, ending a federal enforcement case that began nearly six years ago. Walmart did not admit liability.The Justice Department announced the settlement... Read More about Walmart to Pay $50 Million to Settle DOJ Lawsuit Over Invalid Opioid Prescriptions

Aetna sign outside a corporate office building.

Aetna Sues Florida Radiology Group for ‘Purely Profit-Driven’ Fraud Scheme

CVS-owned healthcare insurer Aetna has filed a lawsuit in the U.S. District Court for the Middle District of Florida against Radiology Partners, Inc. and its affiliate, Mori, Bean & Brooks (MBB). The lawsuit accuses the companies of orchestrating a healthcare fraud scheme that allegedly cost Aetna and their plan sponsors... Read More about Aetna Sues Florida Radiology Group for ‘Purely Profit-Driven’ Fraud Scheme

Exterior view of a CVS pharmacy building with red signage and awnings.

Former CVS Nurse Practitioner Sues for Religious Discrimination After Refusing to Prescribe Birth Control

CVS Health has been hit with a lawsuit for workplace discrimination after allegedly firing a nurse practitioner for refusing to prescribe birth control on religious grounds. According to the complaint, Texas resident J. Robyn Strader worked at a CVS MinuteClinic for six and a half years. CVS granted her religious... Read More about Former CVS Nurse Practitioner Sues for Religious Discrimination After Refusing to Prescribe Birth Control

Kroger store exterior with the company logo prominently displayed.

Kroger, C&S Wholesale Grocers Settle Dispute Over Assets in Failed Albertsons Merger

Kroger and C&S Wholesale Grocers have resolved a lawsuit C&S filed earlier this year seeking a $125 million termination fee connected to Kroger’s unsuccessful attempt to merge with Albertsons. The settlement was disclosed in a joint filing on Friday in Delaware Superior Court. The filing stated that all claims in... Read More about Kroger, C&S Wholesale Grocers Settle Dispute Over Assets in Failed Albertsons Merger

Legal term

Search articles and Legalpedia

Subscribe to Newsletter